Health
The mutation occurs in the epidermal growth factor receptor gene, which regulates cell growth and division across pulmonary tissue. While somatic EGFR mutations acquired during a person’s lifetime are known drivers of non-small cell lung cancer, the T790M germline variant is inherited at birth and present in every cell. Data compiled by the National Cancer Institute shows the mutation occurs in approximately 1 out of every 15,850 people in the United States. Lead study author Dr. Jaclyn LoPiccolo noted that carrying the variant raises lung cancer odds roughly 62 times in never-smokers, compared to about 11 times in individuals with a history of smoking.
Technology
The iPhone Duo uses Super Retina XDR displays on both sides, with ProMotion and Always-On support. Apple rates peak outdoor brightness at 3,000 nits for both screens. A nano-texture finish on the inner panel reduces glare and makes the fold crease less visible, according to Apple. Grade 5 titanium forms the enclosure, while the precision hinge uses more than 100 components. Apple also gives the iPhone Duo an IP68 rating for water and dust resistance. Apple designed iOS 27.1 to work across the phone’s open and closed configurations. Split View lets users run two apps side by side, a first for the iPhone. Users can also open two windows of the same app and save app pairs for later use. The inner screen can show two Home Screen pages and a vertically scrolling Today View. Touch ID sits in the side button and works whether the device is open or folded.
Automotive
German luxury sports car manufacturer Porsche announced an agreement with labor representatives on Monday to reduce its workforce by an additional 5,000 positions by 2035 as part of a restructuring program. The decision brings total planned job eliminations across the company to approximately 9,000 positions, representing roughly 21 percent of its 42,066 workforce. Company leadership confirmed that Porsche to cut 5,000 more jobs under restructuring plan negotiations following months of talks between management and labor councils. The initiative aims to bolster operational efficiency as the vehicle producer confronts declining market share in Asia, elevated global tariffs, and sluggish demand for electric vehicles.